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Oct 29

Synthesis Through Simulation: Generating Coherent Enterprise Data via Scalable Agent-System Interaction

Tool-calling agents have become central to enterprise AI, yet training and evaluating them at scale remains severely constrained due to business and legal restrictions on enterprise systems, data, and database schemas. Tabular data synthesis offers a natural alternative, but its effectiveness is fundamentally limited by structural validity and schema availability, while procedure-based approaches yield the opposite weakness, typically lacking distributional fidelity without per-domain authoring. We introduce **Synthesis Through Simulation** (STS), a **schema--free** data synthesis paradigm in which an LLM agent generates data by executing operations against policy-enforcing APIs within simulated enterprise environments. Because data is generated through the same environment that defines what is valid, STS guarantees structural validity by construction while decoupling validity enforcement from distribution modeling, allowing each to be addressed independently. The **Generalist Populator** (GP), STS's domain-agnostic agent, addresses the remaining challenges of distributional fidelity and synthesis scalability: GP achieves **0.88** average marginal fidelity and **100\% constraint satisfaction** across all ten environments *without access to DB schemas*, while statistical synthesizers are inapplicable to seven due to necessary seed data requirements, and schema-privileged agents fail 82\% of trajectories on airline environment's tightly coupled workflows due to brittle task composition. We open-source the full framework, all ten environments, and generated datasets at https://github.com/SAP/synthesis-through-simulation.

SAP SAP
·
Sep 23 2

From Benchmarks to Business Impact: Deploying IBM Generalist Agent in Enterprise Production

Agents are rapidly advancing in automating digital work, but enterprises face a harder challenge: moving beyond prototypes to deployed systems that deliver measurable business value. This path is complicated by fragmented frameworks, slow development, and the absence of standardized evaluation practices. Generalist agents have emerged as a promising direction, excelling on academic benchmarks and offering flexibility across task types, applications, and modalities. Yet, evidence of their use in production enterprise settings remains limited. This paper reports IBM's experience developing and piloting the Computer Using Generalist Agent (CUGA), which has been open-sourced for the community (https://github.com/cuga-project/cuga-agent). CUGA adopts a hierarchical planner--executor architecture with strong analytical foundations, achieving state-of-the-art performance on AppWorld and WebArena. Beyond benchmarks, it was evaluated in a pilot within the Business-Process-Outsourcing talent acquisition domain, addressing enterprise requirements for scalability, auditability, safety, and governance. To support assessment, we introduce BPO-TA, a 26-task benchmark spanning 13 analytics endpoints. In preliminary evaluations, CUGA approached the accuracy of specialized agents while indicating potential for reducing development time and cost. Our contribution is twofold: presenting early evidence of generalist agents operating at enterprise scale, and distilling technical and organizational lessons from this initial pilot. We outline requirements and next steps for advancing research-grade architectures like CUGA into robust, enterprise-ready systems.

  • 12 authors
·
Oct 27, 2025

Specialist or Generalist? Instruction Tuning for Specific NLP Tasks

The potential of large language models (LLMs) to simultaneously perform a wide range of natural language processing (NLP) tasks has been the subject of extensive research. Although instruction tuning has proven to be a data-efficient method for transforming LLMs into such generalist models, their performance still lags behind specialist models trained exclusively for specific tasks. In this paper, we investigate whether incorporating broad-coverage generalist instruction tuning can contribute to building a specialist model. We hypothesize that its efficacy depends on task specificity and skill requirements. Our experiments assess four target tasks with distinct coverage levels, revealing that integrating generalist instruction tuning consistently enhances model performance when the task coverage is broad. The effect is particularly pronounced when the amount of task-specific training data is limited. Further investigation into three target tasks focusing on different capabilities demonstrates that generalist instruction tuning improves understanding and reasoning abilities. However, for tasks requiring factual knowledge, generalist data containing hallucinatory information may negatively affect the model's performance. Overall, our work provides a systematic guide for developing specialist models with general instruction tuning. Our code and other related resources can be found at https://github.com/DavidFanzz/Generalist_or_Specialist.

  • 5 authors
·
Oct 23, 2023

Towards Generalist Biomedical AI

Medicine is inherently multimodal, with rich data modalities spanning text, imaging, genomics, and more. Generalist biomedical artificial intelligence (AI) systems that flexibly encode, integrate, and interpret this data at scale can potentially enable impactful applications ranging from scientific discovery to care delivery. To enable the development of these models, we first curate MultiMedBench, a new multimodal biomedical benchmark. MultiMedBench encompasses 14 diverse tasks such as medical question answering, mammography and dermatology image interpretation, radiology report generation and summarization, and genomic variant calling. We then introduce Med-PaLM Multimodal (Med-PaLM M), our proof of concept for a generalist biomedical AI system. Med-PaLM M is a large multimodal generative model that flexibly encodes and interprets biomedical data including clinical language, imaging, and genomics with the same set of model weights. Med-PaLM M reaches performance competitive with or exceeding the state of the art on all MultiMedBench tasks, often surpassing specialist models by a wide margin. We also report examples of zero-shot generalization to novel medical concepts and tasks, positive transfer learning across tasks, and emergent zero-shot medical reasoning. To further probe the capabilities and limitations of Med-PaLM M, we conduct a radiologist evaluation of model-generated (and human) chest X-ray reports and observe encouraging performance across model scales. In a side-by-side ranking on 246 retrospective chest X-rays, clinicians express a pairwise preference for Med-PaLM M reports over those produced by radiologists in up to 40.50% of cases, suggesting potential clinical utility. While considerable work is needed to validate these models in real-world use cases, our results represent a milestone towards the development of generalist biomedical AI systems.

  • 32 authors
·
Jul 26, 2023

OpenGCUA: Toward a Fully Open Stack for Generalist Computer Use

Computer use has reached a turning point: the focus is expanding from GUI-only interaction to systems that complete tasks on users' computers through visual and programmatic interfaces. We define a generalist computer-use agent (GCUA) as a system in which the model chooses how to observe, act, and organize its work across visual and programmatic interfaces. Yet frontier implementations, such as GPT-6 Astra's computer-use system, remain largely closed, limiting systematic study of their design. We introduce Open Generalist CUA (OpenGCUA), an ongoing project to develop and open the full stack for GCUAs with the community. This report presents the first release of OpenGCUA. Code execution is a key feature of our agent design: it lets intermediate results determine subsequent operations and enables models to apply their existing programming capabilities directly to computer interaction. We also propose harness-to-model decision transfer, moving selected observations and task-state decisions from fixed harness rules to the model. On OSWorld-v2, our full configuration improves task scores across all eight evaluated models, including GPT-6 Astra and Claude Opus 5, raising mean partial score by +19.6 points and reducing reported steps per task by an average of 53.0% relative to batched GUI-only execution. We release our implementation and prompts, evaluation trajectories from all eight models, and preliminary versions of a real-device harness and a cross-device SDK. The harness addresses real-device challenges not fully captured by benchmarks, while the SDK provides a common programming interface across computers, mobiles and browsers. Across four real macOS tasks under our real-device harness, selected Qwen3.8-Max runs use 19.4 times as many reported reasoning tokens as GPT-6 Astra, highlighting substantial differences between models in real-device execution efficiency.

Tongyi-MAI Tongyi-MAI
·
Oct 14 4

Normal-Abnormal Guided Generalist Anomaly Detection

Generalist Anomaly Detection (GAD) aims to train a unified model on an original domain that can detect anomalies in new target domains. Previous GAD methods primarily use only normal samples as references, overlooking the valuable information contained in anomalous samples that are often available in real-world scenarios. To address this limitation, we propose a more practical approach: normal-abnormal-guided generalist anomaly detection, which leverages both normal and anomalous samples as references to guide anomaly detection across diverse domains. We introduce the Normal-Abnormal Generalist Learning (NAGL) framework, consisting of two key components: Residual Mining (RM) and Anomaly Feature Learning (AFL). RM extracts abnormal patterns from normal-abnormal reference residuals to establish transferable anomaly representations, while AFL adaptively learns anomaly features in query images through residual mapping to identify instance-aware anomalies. Our approach effectively utilizes both normal and anomalous references for more accurate and efficient cross-domain anomaly detection. Extensive experiments across multiple benchmarks demonstrate that our method significantly outperforms existing GAD approaches. This work represents the first to adopt a mixture of normal and abnormal samples as references in generalist anomaly detection. The code and datasets are available at https://github.com/JasonKyng/NAGL.

  • 4 authors
·
Oct 1, 2025

Can Generalist Foundation Models Outcompete Special-Purpose Tuning? Case Study in Medicine

Generalist foundation models such as GPT-4 have displayed surprising capabilities in a wide variety of domains and tasks. Yet, there is a prevalent assumption that they cannot match specialist capabilities of fine-tuned models. For example, most explorations to date on medical competency benchmarks have leveraged domain-specific training, as exemplified by efforts on BioGPT and Med-PaLM. We build on a prior study of GPT-4's capabilities on medical challenge benchmarks in the absence of special training. Rather than using simple prompting to highlight the model's out-of-the-box capabilities, we perform a systematic exploration of prompt engineering. We find that prompting innovation can unlock deeper specialist capabilities and show that GPT-4 easily tops prior leading results for medical benchmarks. The prompting methods we explore are general purpose, and make no specific use of domain expertise, removing the need for expert-curated content. Our experimental design carefully controls for overfitting during the prompt engineering process. We introduce Medprompt, based on a composition of several prompting strategies. With Medprompt, GPT-4 achieves state-of-the-art results on all nine of the benchmark datasets in the MultiMedQA suite. The method outperforms leading specialist models such as Med-PaLM 2 by a significant margin with an order of magnitude fewer calls to the model. Steering GPT-4 with Medprompt achieves a 27% reduction in error rate on the MedQA dataset over the best methods to date achieved with specialist models and surpasses a score of 90% for the first time. Beyond medical problems, we show the power of Medprompt to generalize to other domains and provide evidence for the broad applicability of the approach via studies of the strategy on exams in electrical engineering, machine learning, philosophy, accounting, law, nursing, and clinical psychology.

  • 18 authors
·
Nov 27, 2023

Chameleon: A Data-Efficient Generalist for Dense Visual Prediction in the Wild

Large language models have evolved data-efficient generalists, benefiting from the universal language interface and large-scale pre-training. However, constructing a data-efficient generalist for dense visual prediction presents a distinct challenge due to the variation in label structures across different tasks. Consequently, generalization to unseen dense prediction tasks in the low-data regime is not straightforward and has received less attention from previous vision generalists. In this study, we explore a universal model that can flexibly adapt to unseen dense label structures with a few examples, enabling it to serve as a data-efficient vision generalist in diverse real-world scenarios. To this end, we base our method on a powerful meta-learning framework and explore several axes to improve its performance and versatility for real-world problems, such as flexible adaptation mechanisms and scalability. We evaluate our model across a spectrum of unseen real-world scenarios where low-shot learning is desirable, including video, 3D, medical, biological, and user-interactive tasks. Equipped with a generic architecture and an effective adaptation mechanism, our model flexibly adapts to all of these tasks with at most 50 labeled images, showcasing a significant advancement over existing data-efficient generalist approaches. Codes are available at https://github.com/GitGyun/chameleon.

  • 5 authors
·
Apr 29, 2024

Stimulating Imagination: Towards General-purpose "Something Something Placement"

General-purpose object placement is a fundamental capability of an intelligent generalist robot: being capable of rearranging objects following precise human instructions even in novel environments. This work is dedicated to achieving general-purpose object placement with ``something something'' instructions. Specifically, we break the entire process down into three parts, including object localization, goal imagination and robot control, and propose a method named SPORT. SPORT leverages a pre-trained large vision model for broad semantic reasoning about objects, and learns a diffusion-based pose estimator to ensure physically-realistic results in 3D space. Only object types (movable or reference) are communicated between these two parts, which brings two benefits. One is that we can fully leverage the powerful ability of open-set object recognition and localization since no specific fine-tuning is needed for the robotic scenario. Moreover, the diffusion-based estimator only need to ``imagine" the object poses after the placement, while no necessity for their semantic information. Thus the training burden is greatly reduced and no massive training is required. The training data for the goal pose estimation is collected in simulation and annotated by using GPT-4. Experimental results demonstrate the effectiveness of our approach. SPORT can not only generate promising 3D goal poses for unseen simulated objects, but also be seamlessly applied to real-world settings.

  • 6 authors
·
Jul 20, 2025

Rethinking Interactive Image Segmentation with Low Latency, High Quality, and Diverse Prompts

The goal of interactive image segmentation is to delineate specific regions within an image via visual or language prompts. Low-latency and high-quality interactive segmentation with diverse prompts remain challenging for existing specialist and generalist models. Specialist models, with their limited prompts and task-specific designs, experience high latency because the image must be recomputed every time the prompt is updated, due to the joint encoding of image and visual prompts. Generalist models, exemplified by the Segment Anything Model (SAM), have recently excelled in prompt diversity and efficiency, lifting image segmentation to the foundation model era. However, for high-quality segmentations, SAM still lags behind state-of-the-art specialist models despite SAM being trained with x100 more segmentation masks. In this work, we delve deep into the architectural differences between the two types of models. We observe that dense representation and fusion of visual prompts are the key design choices contributing to the high segmentation quality of specialist models. In light of this, we reintroduce this dense design into the generalist models, to facilitate the development of generalist models with high segmentation quality. To densely represent diverse visual prompts, we propose to use a dense map to capture five types: clicks, boxes, polygons, scribbles, and masks. Thus, we propose SegNext, a next-generation interactive segmentation approach offering low latency, high quality, and diverse prompt support. Our method outperforms current state-of-the-art methods on HQSeg-44K and DAVIS, both quantitatively and qualitatively.

  • 4 authors
·
Mar 30, 2024

Robust Finetuning of Vision-Language-Action Robot Policies via Parameter Merging

Generalist robot policies, trained on large and diverse datasets, have demonstrated the ability to generalize across a wide spectrum of behaviors, enabling a single policy to act in varied real-world environments. However, they still fall short on new tasks not covered in the training data. When finetuned on limited demonstrations of a new task, these policies often overfit to the specific demonstrations--not only losing their prior abilities to solve a wide variety of generalist tasks but also failing to generalize within the new task itself. In this work, we aim to develop a method that preserves the generalization capabilities of the generalist policy during finetuning, allowing a single policy to robustly incorporate a new skill into its repertoire. Our goal is a single policy that both learns to generalize to variations of the new task and retains the broad competencies gained from pretraining. We show that this can be achieved through a simple yet effective strategy: interpolating the weights of a finetuned model with that of the pretrained model. We show, across extensive simulated and real-world experiments, that such model merging produces a single model that inherits the generalist abilities of the base model and learns to solve the new task robustly, outperforming both the pretrained and finetuned model on out-of-distribution variations of the new task. Moreover, we show that model merging performance scales with the amount of pretraining data, and enables continual acquisition of new skills in a lifelong learning setting, without sacrificing previously learned generalist abilities.

  • 5 authors
·
Dec 9, 2025