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Jan 5

Why Registration Quality Matters: Enhancing sCT Synthesis with IMPACT-Based Registration

We participated in the SynthRAD2025 challenge (Tasks 1 and 2) with a unified pipeline for synthetic CT (sCT) generation from MRI and CBCT, implemented using the KonfAI framework. Our model is a 2.5D U-Net++ with a ResNet-34 encoder, trained jointly across anatomical regions and fine-tuned per region. The loss function combined pixel-wise L1 loss with IMPACT-Synth, a perceptual loss derived from SAM and TotalSegmentator to enhance structural fidelity. Training was performed using AdamW (initial learning rate = 0.001, halved every 25k steps) on patch-based, normalized, body-masked inputs (320x320 for MRI, 256x256 for CBCT), with random flipping as the only augmentation. No post-processing was applied. Final predictions leveraged test-time augmentation and five-fold ensembling. The best model was selected based on validation MAE. Two registration strategies were evaluated: (i) Elastix with mutual information, consistent with the challenge pipeline, and (ii) IMPACT, a feature-based similarity metric leveraging pretrained segmentation networks. On the local test sets, IMPACT-based registration achieved more accurate and anatomically consistent alignments than mutual-information-based registration, resulting in improved sCT synthesis with lower MAE and more realistic anatomical structures. On the public validation set, however, models trained with Elastix-aligned data achieved higher scores, reflecting a registration bias favoring alignment strategies consistent with the evaluation pipeline. This highlights how registration errors can propagate into supervised learning, influencing both training and evaluation, and potentially inflating performance metrics at the expense of anatomical fidelity. By promoting anatomically consistent alignment, IMPACT helps mitigate this bias and supports the development of more robust and generalizable sCT synthesis models.

  • 4 authors
·
Oct 24, 2025

EvolvR: Self-Evolving Pairwise Reasoning for Story Evaluation to Enhance Generation

Although the effectiveness of Large Language Models (LLMs) as judges (LLM-as-a-judge) has been validated, their performance remains limited in open-ended tasks, particularly in story evaluation. Accurate story evaluation is crucial not only for assisting human quality judgment but also for providing key signals to guide story generation. However, existing methods face a dilemma: prompt engineering for closed-source models suffers from poor adaptability, while fine-tuning approaches for open-source models lack the rigorous reasoning capabilities essential for story evaluation. To address this, we propose the Self-Evolving Pairwise Reasoning (EvolvR) framework. Grounded in pairwise comparison, the framework first self-synthesizes score-aligned Chain-of-Thought (CoT) data via a multi-persona strategy. To ensure data quality, these raw CoTs undergo a self-filtering process, utilizing multi-agents to guarantee their logical rigor and robustness. Finally, the evaluator trained on the refined data is deployed as a reward model to guide the story generation task. Experimental results demonstrate that our framework achieves state-of-the-art (SOTA) performance on three evaluation benchmarks including StoryER, HANNA and OpenMEVA. Furthermore, when served as a reward model, it significantly enhances the quality of generated stories, thereby fully validating the superiority of our self-evolving approach.

  • 9 authors
·
Aug 8, 2025

P-Aligner: Enabling Pre-Alignment of Language Models via Principled Instruction Synthesis

Large Language Models (LLMs) are expected to produce safe, helpful, and honest content during interaction with human users, but they frequently fail to align with such values when given flawed instructions, e.g., missing context, ambiguous directives, or inappropriate tone, leaving substantial room for improvement along multiple dimensions. A cost-effective yet high-impact way is to pre-align instructions before the model begins decoding. Existing approaches either rely on prohibitive test-time search costs or end-to-end model rewrite, which is powered by a customized training corpus with unclear objectives. In this work, we demonstrate that the goal of efficient and effective preference alignment can be achieved by P-Aligner, a lightweight module generating instructions that preserve the original intents while being expressed in a more human-preferred form. P-Aligner is trained on UltraPrompt, a new dataset synthesized via a proposed principle-guided pipeline using Monte-Carlo Tree Search, which systematically explores the space of candidate instructions that are closely tied to human preference. Experiments across different methods show that P-Aligner generally outperforms strong baselines across various models and benchmarks, including average win-rate gains of 28.35% and 8.69% on GPT-4-turbo and Gemma-2-SimPO, respectively. Further analyses validate its effectiveness and efficiency through multiple perspectives, including data quality, search strategies, iterative deployment, and time overhead.

  • 9 authors
·
Aug 6, 2025