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id
stringclasses
8 values
condition_family
stringclasses
8 values
pre_state_vector_summary
stringclasses
8 values
pre_trajectory_summary
stringclasses
8 values
intervention
stringclasses
8 values
intervention_class
stringclasses
6 values
post_state_vector_summary
stringclasses
8 values
post_trajectory_summary
stringclasses
8 values
observed_change_window
stringclasses
8 values
pre_basin_signature
stringclasses
8 values
post_basin_signature
stringclasses
8 values
transition_pathway_summary
stringclasses
8 values
coherence_gain_evidence
stringclasses
8 values
shift_class
stringclasses
3 values
relapse_watchouts
stringclasses
8 values
notes
stringclasses
8 values
constraints
stringclasses
1 value
gold_checklist
stringclasses
1 value
IBSM-001
metabolic
A1c 8.2; fasting insulin high; TG high; sleep fragmented; activity low
12 month plateau with slow upward creep
Time restricted eating plus sleep regularization
lifestyle
A1c 6.9; TG down; sleep stable; activity higher
3 month steady improvement then stable
6 months
Hyperinsulinemia plus dyslipidemia plus circadian disruption
Lower insulin demand plus stable circadian rhythm plus improved activity tolerance
Sleep stabilizes then appetite timing improves then glycemic markers follow
Multi-modal alignment in sleep plus labs plus behavior
Sustained shift
Stress relapse and sleep collapse
Shows multi axis coherence gain
Under 240 words.
pre+post+path+evidence+class
IBSM-002
neuroimmune
PEM present; HRV low; orthostatic symptoms; labs mostly normal
Relapsing crashes after exertion
Pacing protocol plus autonomic rehab
behavioral
Crashes reduced; HRV modestly improved; function higher
2 month improvement with fewer rebounds
4 months
Exertion to crash to deconditioning loop
Lower crash frequency plus higher baseline stability
Reduced exertion spikes then gradual tolerance rebuild
Fewer crashes plus improved digital phenotype stability
Partial shift
Overreach triggers crash
Not full exit but basin shallower
Under 240 words.
pre+post+path+evidence+class
IBSM-003
respiratory
Eosinophils high; wheeze frequent; steroid bursts
Flares with allergens
Biologic anti IL5 therapy
drug
Eosinophils normalize; flares rare; steroid need drops
Sustained improvement
9 months
Eosinophilic airway inflammation basin
Controlled eosinophilic inflammation basin
Biologic reduces eosinophils then airway reactivity drops
Labs plus symptom reduction with fewer steroids
Sustained shift
Stopping drug leads relapse
Drug dependent stability
Under 240 words.
pre+post+path+evidence+class
IBSM-004
cardiac
AF episodes weekly; sleep apnea untreated; HRV low
Episodes triggered by poor sleep
CPAP plus weight loss
device plus lifestyle
AF episodes rare; sleep stable; HRV improves
Steady improvement
8 months
Sleep disruption driven trigger basin
Lower trigger susceptibility basin
Sleep correction reduces triggers then rhythm stabilizes
Trigger reduction plus durable rhythm change
Sustained shift
CPAP nonadherence
Shows leverage through upstream driver
Under 240 words.
pre+post+path+evidence+class
IBSM-005
psycho_somatic
Insomnia severe; GI dysmotility; anxiety spikes; cortisol AM high
Chronic hyperarousal
Trauma focused therapy plus sleep protocol
therapy plus behavioral
Sleep improves; GI symptoms reduce; anxiety spikes less
Gradual improvement then stable
7 months
Hyperarousal loop basin
Regulated autonomic tone basin
Therapy reduces arousal reactivity then sleep consolidates then gut stabilizes
Multi domain improvement not just symptom masking
Sustained shift
Acute stressor may reactivate
Good example of cross system shift
Under 240 words.
pre+post+path+evidence+class
IBSM-006
autoimmune
Joint pain flares; rash episodic; CRP often normal; fatigue
Flares every 6 to 8 weeks
Steroid burst only
drug
Flares stop briefly then return
Relief then rebound
3 months
Immune flare basin
Same basin with suppressed expression
Symptom suppression without loop change
No durable lab or frequency change
No shift
Steroid dependency
Perturbation not transition
Under 240 words.
pre+post+path+evidence+class
IBSM-007
renal
Proteinuria rising; BP rising; eGFR slowly falling
Monotone decline
ACE inhibitor plus sodium restriction
drug plus lifestyle
Proteinuria down; BP controlled; eGFR slope slows
Stabilization
10 months
Hypertension damage reinforcement basin
Slower decline basin
BP control reduces ongoing damage then renal markers stabilize
Slope change plus multi marker stabilization
Partial shift
Adherence loss and volume overload
Shift in slope not full exit
Under 240 words.
pre+post+path+evidence+class
IBSM-008
infectious
Periodic fevers; innate spikes; cultures negative
Monthly cycles
Targeted IL1 blockade
drug
Cycles stop; markers normalize; function improves
Sustained
12 months
Autoinflammatory cycle basin
Controlled innate tone basin
Blockade interrupts cycle and stabilizes baseline
Cycle cessation plus marker normalization
Sustained shift
Stop drug relapse
Clear basin transition with dependency
Under 240 words.
pre+post+path+evidence+class

What this dataset tests

Whether an intervention produces a real basin shift
or only a temporary perturbation.

Required outputs

  • pre basin signature
  • post basin signature
  • transition pathway summary
  • coherence gain evidence
  • shift class
  • relapse watchouts

Shift classes

  • no shift
  • partial shift
  • sustained shift
  • negative shift

Use case

Atlas layer for basin transition therapy planning
and adaptive pathway navigation.

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